PG电子

1. Tian X*, Liu X*, Ding J, Wang F, Wang K, Liu J, Wei Z, Hao X, Li Y, Wei X, Zhang H, Sui J. An anti-CD98 antibody displaying pH-dependent Fc-mediated tumour-specific activity against multiple cancers in CD98-humanized mice. Nat Biomed Eng 2023, 7 (1): 8-23.

2. Liu X*, Tian X*, Hao X, Zhang H, Wang K, Wei Z, Wei X, Li Y, Sui J. A cross-reactive pH-dependent EGFR antibody with improved tumor selectivity and penetration obtained by structure-guided engineering. Mol Ther Oncolytics 2022, 27: 256-269.

3. Yang F, Zhao L, Wei Z, Yang Y, Liu J, Li Y, Tian X, Liu X, and Sui J. A Cross-Species Reactive TIGIT-Blocking Antibody Fc Dependently Confers Potent Antitumor Effects. J Immunol 2020, 205(8): 2156-2168

PG电子-PG电子官方直营平台 /北京生命科学研究所抗体中心为研究所各实验室的基础科学研究提供多克隆抗体、单克隆抗体和单域抗体等多种抗体的筛选、制备、评估等服务。本中心还可以协助重组蛋白的表达纯化以及活性测定等工作。此外，本中心对靶向病毒、肿瘤相关蛋白、免疫检查点的抗体开发与研究有一定基础，并期待与各实验室合作开发针对其他疾病的诊断或治疗性抗体。

Antibody Center of National Institute of Biological Sciences, Beijing is dedicated to provide services related to development and evaluation of various types of antibodies (including polyclonal antibody, monoclonal antibody, single-chain Fv antibody, bi-specific antibody, and nanobody) for different experiments. We can also assist in design, production, and assessment of fusion proteins. Moreover, we have experience in developing and investigating antibodies targeting viruses, tumor-associated proteins, and immune checkpoints, and we look forward to cooperate with other research groups to develop therapeutic or diagnostic antibodies for other diseases.